Letrozole

ATC L02BG04 · WHO DDD 2.5 mg (oral) · 2.5 mg tablet

Class: Hormone antagonists (cancer). ATC code L02BG04 stands for "letrozole" in the WHO index, whose DDD is 2.5 mg by the oral route [1].

WHO Model List of Essential Medicines 2025: listed, complementary list, and covered as a therapeutic alternative under the Anastrozole listing [2].

Indications on the WHO list (3)

The WHO electronic list states that the 2025 PDF lists are binding: adults’ list, children’s list.

Summary by country, in euros at the ECB rate of 9 October 2026 [3]
CountryPacksKind of figure Cost per DDDAnnual cost at the WHO standard dose
France 15 List price €1.12 €407.10
Spain 30 List price €3.07 €1,121
United Kingdom 1 Reimbursement tariff €0.09 €32.91 £27.90

Names, authorisations and literature

Trade names (36)
France (13)
FEMARA, LETROZOLE ACCORD HEALTHCARE, LETROZOLE ALMUS, LETROZOLE ARROW LAB, LETROZOLE BIOGARAN, LETROZOLE CRISTERS PHARMA, LETROZOLE EG, LETROZOLE EVOLUGEN, LETROZOLE SANDOZ, LETROZOLE TEVA, LETROZOLE VIATRIS, LETROZOLE ZENTIVA, LETROZOLE ZYDUS [4]
Spain (23)
FEMARA, GALDAR, LETROZOL ACCORD, LETROZOL ALMUS PHARMA, LETROZOL ALTER, LETROZOL AUROVITAS, LETROZOL BLUEFISH, LETROZOL CINFA, LETROZOL COMBIX, LETROZOL DR. REDDYS, LETROZOL EDIGEN, LETROZOL KERN PHARMA, LETROZOL MABO, LETROZOL NORMON, LETROZOL PENSA PHARMA, LETROZOL SANDOZ, LETROZOL STADA, LETROZOL TARBIS FARMA, LETROZOL TECNIGEN, LETROZOL TEVAGEN, LETROZOL VIATRIS, LOXIFAN, SYBALI [5]

Links lead to the official product page: the EPAR for the European Union, the public medicines database for France, the CIMA summary of product characteristics for Spain, the dm+d for the United Kingdom. An asterisk marks a name taken from the DysNet register only.

European public assessment reports, EPAR (0)

The European Medicines Agency's list holds no medicine with ATC code L02BG04: this medicine has no EPAR [6].

Literature (PubMed, 5,427 papers)

PubMed counts 5,427 papers on this medicine [7]. The selection gives the most recent of each type; the Method page says how it is made. See the search in PubMed ↗

Cochrane reviews (6)

  • Lepine S, et al. Ovarian surgery for symptom relief in women with polycystic ovary syndrome. Cochrane Database Syst Rev. 2017. PubMed 29125183 ↗ doi ↗
  • McGrath N, et al. Aromatase inhibitors for short stature in male children and adolescents. Cochrane Database Syst Rev. 2015. PubMed 26447646 ↗ doi ↗
  • Song H, et al. Aromatase inhibitors for uterine fibroids. Cochrane Database Syst Rev. 2013. PubMed 24151065 ↗ doi ↗
  • Gibson L, et al. Aromatase inhibitors for treatment of advanced breast cancer in postmenopausal women. Cochrane Database Syst Rev. 2009. PubMed 19821307 ↗ doi ↗
  • Gibson LJ, et al. Aromatase inhibitors for treatment of advanced breast cancer in postmenopausal women. Cochrane Database Syst Rev. 2007. PubMed 17253488 ↗ doi ↗

All 6 results in PubMed ↗

Systematic reviews and meta-analyses (103)
  • Liang C, et al. Safety profile of letrozole in the real world: a disproportionality analysis of FAERS database and systematic review of case reports. Expert Opin Drug Saf. 2026. PubMed 40590361 ↗ doi ↗
  • Erden M, et al. Letrozole-based stimulation versus programmed cycle for frozen embryo transfer in women with polyendocrine metabolic ovarian syndrome: a systematic review and meta-analysis of randomized controlled trials. Reprod Biomed Online. 2026. PubMed 42810244 ↗ doi ↗
  • Tartarini C, et al. Letrozole in Paediatric Females for Peripheral Precocious Puberty: A Systematic Review of Efficacy and Safety. J Clin Endocrinol Metab. 2026. PubMed 42711790 ↗ doi ↗
  • Oloriegbe MG, et al. Tailoring Oncofertility to Breast Cancer Subtype: A Systematic Review of Fertility Preservation Strategies in Premenopausal Women. Cancers (Basel). 2026. PubMed 42352431 ↗ doi ↗
  • Vidakovic E, et al. The role of sex hormones in neurological and functional recovery following spinal cord injury in females: a systematic review of the literature. Spinal Cord. 2026. PubMed 41965782 ↗ doi ↗

All 103 results in PubMed ↗

Practice guidelines (7)
  • Pierre ME, et al. Expert consensus: Profiling and management of advanced or metastatic epithelial ovarian cancer. Rev Colomb Obstet Ginecol. 2024. PubMed 39013199 ↗ doi ↗
  • ACOG Committee Opinion No. 738: Aromatase Inhibitors in Gynecologic Practice. Obstet Gynecol. 2018. PubMed 29794680 ↗ doi ↗
  • ACOG Committee Opinion No. 738 Summary: Aromatase Inhibitors in Gynecologic Practice. Obstet Gynecol. 2018. PubMed 29794673 ↗ doi ↗

All 7 results in PubMed ↗

Health technology assessments (5)

The opinions of the assessment bodies of the pilot countries and of Germany, with a link to each opinion. The status shown is the one each body publishes.

France, HAS Transparency Committee (3)

SMR: actual clinical benefit. ASMR: improvement in actual clinical benefit, from I (major) to V (none). Opinions taken from the BDPM [4].

  • CT-14424 · 2 December 2015 · Extension d'indication · SMR Important · ASMR V · FEMARA
    Wording of the opinion, in French

    SMR : Le service médical rendu par FEMARA est important dans le traitement néoadjuvant chez la femme ménopausée avec des récepteurs hormonaux positifs présentant un cancer du sein HER-2 négatif lorsque la chimiothérapie n’est pas adaptée et que la chirurgie immédiate n’est pas indiquée.

    ASMR : Compte tenu de la transposabilité non assurée des données issues de l’étude pivot en raison de l’absence de prise en compte du statut HER2 et de l’éligibilité à la chimiothérapie dans l’inclusion des patientes, la Commission considère que FEMARA n’apporte pas d’Amélioration du Service Médical Rendu (ASMR V) par rapport à la stratégie actuelle de prise en charge de ces patientes.

  • CT-14362 · 2 December 2015 · Renouvellement d'inscription (CT) · SMR Important · FEMARA
    Wording of the opinion, in French

    SMR : Le service médical rendu par FEMARA reste important dans : • le traitement adjuvant du cancer du sein invasif à un stade précoce chez la femme ménopausée avec des récepteurs hormonaux positifs . • la prolongation du traitement adjuvant du cancer du sein hormono-dépendant invasif chez la femme ménopausée ayant préalablement reçu un traitement adjuvant standard par le tamoxifène pendant 5 ans . • le traitement de première intention du cancer du sein hormono-dépendant à un stade avancé chez la femme ménopausée . • et le traitement du cancer du sein à un stade avancé après rechute ou progression de la maladie chez la femme ménopausée (statut endocrinien de ménopause naturelle ou artificielle) ayant été préalablement traitée par des antiestrogènes.

  • CT-3754 · 3 January 2007 · Extension d'indication · ASMR III · FEMARA
    Wording of the opinion, in French

    ASMR : FEMARA partage avec ARIMIDEX une ASMR modérée (de niveau III) en termes d'efficacité et de tolérance par rapport au tamoxifène dans l'indication traitement adjuvant du cancer du sein à un stade précoce chez la femme ménopausée.

England, NICE (0)

NICE has published no technology appraisal that names this medicine among the technologies appraised [8].

Scotland, SMC (2)
  • SMC 251/06 · 8 May 2006 · letrozole (Femara) · restricted · Full
    Indication

    Adjuvant treatment of postmenopausal women with hormone receptor positive invasive early breast cancer

  • SMC 152/05 · 7 March 2005 · Letrozole (Femara®) · restricted · Full
    Indication

    Invasive early breast cancer in postmenopausal women who have already received standard tamoxifen therapy.

  • SMC advice [9]
Germany, G-BA (0)

The G-BA has run no early benefit assessment (AMNOG) of this medicine on its own [10].

Spain, AEMPS therapeutic positioning reports (0)

The AEMPS database of therapeutic positioning reports holds no report on this medicine [11].

How the figure is computed

Example, France: the pack LETROZOLE ARROW LAB 2,5 mg, comprimé pelliculé, plaquette(s) PVC PVDC aluminium de 30 comprimé(s), costs €33.46. It holds 75 mg, which is 30 DDD. The cost per DDD is €33.46 ÷ 30 = €1.12, and the annual cost at the WHO standard dose, list price, is that cost × 365 = €407.10.

France

Public price in France, including VAT and the per-pack dispensing fee. Source [4], read on 9 October 2026. ATC match: through the active substance (BDPM substance code), since the BDPM gives no ATC code.

Show the 15 packs
ProductPackPrice DDD per packCost per DDDAnnual cost at the WHO standard doseSource line
LETROZOLE ARROW LAB 2,5 mg, comprimé pelliculéEUGIA PHARMA (MALTA) (MALTE) plaquette(s) PVC PVDC aluminium de 30 comprimé(s) €33.46 30 €1.12 €407.10 CIS 60293216 / CIP13 3400930217191substance code 26682 (LÉTROZOLE) in CIS_COMPO_bdpm
LETROZOLE EG 2,5 mg, comprimé pelliculéEG LABO - LABORATOIRES EUROGENERICS plaquette(s) PVC-Aluminium de 30 comprimé(s) €33.46 30 €1.12 €407.10 CIS 60791099 / CIP13 3400949452460substance code 26682 (LÉTROZOLE) in CIS_COMPO_bdpm
LETROZOLE ZYDUS 2,5 mg, comprimé pelliculéZYDUS FRANCE plaquette(s) thermoformée(s) PVDC PVC aluminium de 30 comprimé(s) €33.46 30 €1.12 €407.10 CIS 63255320 / CIP13 3400939851952substance code 26682 (LÉTROZOLE) in CIS_COMPO_bdpm
FEMARA 2,5 mg, comprimé pelliculéNOVARTIS PHARMA plaquette(s) thermoformée(s) PVC polyéthylène PVDC aluminium de 30 comprimé(s) €33.46 30 €1.12 €407.10 CIS 64492112 / CIP13 3400934147425substance code 26682 (LÉTROZOLE) in CIS_COMPO_bdpm
FEMARA 2,5 mg, comprimé pelliculéBB FARMA (ITALIE) plaquette(s) thermoformée(s) PVC polyéthylène PVDC aluminium de 30 comprimé(s) €33.46 30 €1.12 €407.10 CIS 64721664 / CIP13 3400949000401substance code 26682 (LÉTROZOLE) in CIS_COMPO_bdpm
FEMARA 2,5 mg, comprimé pelliculéBB FARMA (ITALIE) plaquette(s) thermoformée(s) PVC polyéthylène PVDC aluminium de 30 comprimé(s) €33.46 30 €1.12 €407.10 CIS 64722435 / CIP13 3400949000944substance code 26682 (LÉTROZOLE) in CIS_COMPO_bdpm
LETROZOLE EVOLUGEN 2,5 mg, comprimé pelliculéEVOLUPHARM plaquette(s) thermoformée(s) PVC aluminium de 30 comprimé(s) €33.46 30 €1.12 €407.10 CIS 64849151 / CIP13 3400922136165substance code 26682 (LÉTROZOLE) in CIS_COMPO_bdpm
LETROZOLE CRISTERS PHARMA 2,5 mg, comprimé pelliculéSUN PHARMACEUTICAL INDUSTRIES EUROPE (PAYS BAS) plaquette(s) thermoformée(s) PVC-Aluminium de 30 comprimé(s) €33.46 30 €1.12 €407.10 CIS 65035967 / CIP13 3400949855827substance code 26682 (LÉTROZOLE) in CIS_COMPO_bdpm
LETROZOLE TEVA 2,5 mg, comprimé pelliculéTEVA SANTE plaquette(s) PVC PVDC aluminium de 30 comprimé(s) €33.46 30 €1.12 €407.10 CIS 65478037 / CIP13 3400938294088substance code 26682 (LÉTROZOLE) in CIS_COMPO_bdpm
LETROZOLE VIATRIS 2,5 mg, comprimé pelliculéVIATRIS SANTE 30 plaquette(s) PVC PVDC aluminium de 1 comprimé(s) €33.46 30 €1.12 €407.10 CIS 66801276 / CIP13 3400949916542substance code 26682 (LÉTROZOLE) in CIS_COMPO_bdpm
LETROZOLE BIOGARAN 2,5 mg, comprimé peliculéBIOGARAN plaquette(s) PVC-Aluminium de 30 comprimé(s) €33.46 30 €1.12 €407.10 CIS 66935695 / CIP13 3400949188123substance code 26682 (LÉTROZOLE) in CIS_COMPO_bdpm
LETROZOLE ALMUS 2,5 mg, comprimé pelliculéALMUS FRANCE plaquette(s) aluminium PVDC de 30 comprimé(s) €33.46 30 €1.12 €407.10 CIS 67399300 / CIP13 3400930162309substance code 26682 (LÉTROZOLE) in CIS_COMPO_bdpm
FEMARA 2,5 mg, comprimé pelliculéDIFARMED (ESPAGNE) plaquette(s) thermoformée(s) PVC polyéthylène PVDC aluminium de 30 comprimé(s) €33.46 30 €1.12 €407.10 CIS 68432511 / CIP13 3400949002139substance code 26682 (LÉTROZOLE) in CIS_COMPO_bdpm
LETROZOLE ZENTIVA 2,5 mg, comprimé pelliculéZENTIVA FRANCE plaquette(s) thermoformée(s) PVC polyéthylène PVDC aluminium de 30 comprimé(s) €33.46 30 €1.12 €407.10 CIS 69034542 / CIP13 3400949140855substance code 26682 (LÉTROZOLE) in CIS_COMPO_bdpm
LETROZOLE ACCORD HEALTHCARE 2,5 mg, comprimé pelliculéACCORD HEALTHCARE FRANCE plaquette(s) thermoformée(s) PVC PVDC aluminium de 30 comprimé(s) €33.46 30 €1.12 €407.10 CIS 69489312 / CIP13 3400939439372substance code 26682 (LÉTROZOLE) in CIS_COMPO_bdpm

Spain

Retail price including VAT (PVP IVA). Source [12][5], read on 9 October 2026. ATC match: ATC code of each national code, checked in CIMA.

Show the 30 packs
ProductPackPrice DDD per packCost per DDDAnnual cost at the WHO standard doseSource line
LETROZOL SANDOZ 2,5 mg comprimidos recubiertos con pelicula , 30 comprimidosSANDOZ FARMACEUTICA, S.A 30 comprimidos €92.10 30 €3.07 €1,121 Código Nacional 652223AEMPS CIMA, registration 70933
LETROZOL NORMON 2,5 mg comprimidos recubiertos con pelicula , 30 comprimidosNORMON S.A. 30 comprimidos €92.10 30 €3.07 €1,121 Código Nacional 661065AEMPS CIMA, registration 69862
LETROZOL TECNIGEN 2,5 mg comprimidos recubiertos con pelicula , 30 comprimidosTECNIMEDE ESPAÑA INDUSTRIA FARMACEUTICA S.A. 30 comprimidos €92.10 30 €3.07 €1,121 Código Nacional 663105AEMPS CIMA, registration 70995
GALDAR 2,5 mg comprimidos recubiertos con pelicula , 30 comprimidosGP-PHARM,S.A 30 comprimidos €92.10 30 €3.07 €1,121 Código Nacional 663137AEMPS CIMA, registration 71058
LETROZOL STADA 2,5 mg comprimidos recubiertos con pelicula , 30 comprimidosSTADA, S.L 30 comprimidos €92.10 30 €3.07 €1,121 Código Nacional 663247AEMPS CIMA, registration 70305
LETROZOL EDIGEN 2,5 mg COMPRIMIDOS RECUBIERTOS CON PELICULA EFG , 30 comprimidosARISTO PHARMA IBERIA, S.L. 30 comprimidos €92.10 30 €3.07 €1,121 Código Nacional 663405AEMPS CIMA, registration 70854
LETROZOL KERN PHARMA 2,5 mg comprimidos recubiertos con pelicula , 30 comprimidos (AL/PVC/PVDC Transparente)KERN PHARMA, S.L. 30 comprimidos €92.10 30 €3.07 €1,121 Código Nacional 664309AEMPS CIMA, registration 71661
LETROZOL ALTER 2,5 mg COMPRIMIDOS RECUBIERTOS CON PELICULA EFG , 30 comprimidosALTER S.A. 30 comprimidos €92.10 30 €3.07 €1,121 Código Nacional 665063AEMPS CIMA, registration 72124
LETROZOL CINFA 2,5 mg comprimidos recubiertos con pelicula , 30 comprimidosCINFA S.A. 30 comprimidos €92.10 30 €3.07 €1,121 Código Nacional 665064AEMPS CIMA, registration 72125
LETROZOL ACCORD 2,5 mg comprimidos recubiertos con pelicula , 30 comprimidosACCORD HEALTHCARE, S.L.U 30 comprimidos €92.10 30 €3.07 €1,121 Código Nacional 665152AEMPS CIMA, registration 70745
FEMARA 2.5MG 30 COMPRIMIDOS LAQUEADOSNOVARTIS FARMACEUTICA S.A. 30 COMPRIMIDOS €92.10 30 €3.07 €1,121 Código Nacional 669622AEMPS CIMA, registration 61628
LETROZOL TEVAGEN 2,5 mg COMPRIMIDOS RECUBIERTOS CON PELICULA , 30 comprimidosTEVA PHARMA, S.L.U 30 comprimidos €92.10 30 €3.07 €1,121 Código Nacional 671455AEMPS CIMA, registration 72500
LETROZOL DR. REDDYS 2.5 MG COMPRIMIDOS RECUBIERTOS CON PELICULA EFG. 30 comprimidosREDDY PHARMA IBERIA, S.A 30 comprimidos €92.10 30 €3.07 €1,121 Código Nacional 674543AEMPS CIMA, registration 72683
LETROZOL COMBIX 2,5 mg comprimidos recubiertos con pelicula , 30 comprimidosCOMBIX, S.L.U 30 comprimidos €92.10 30 €3.07 €1,121 Código Nacional 681292AEMPS CIMA, registration 74256
LETROZOL BLUEFISH 2,5 mg COMPRIMIDOS RECUBIERTOS CON PELICULA EFG, 30 comprimidosBLUEFISH PHARMA, S.L.U 30 comprimidos €92.10 30 €3.07 €1,121 Código Nacional 684931AEMPS CIMA, registration 74858
LETROZOL PENSA PHARMA 2,5 MG COMPRIMIDOS RECUBIERTOS CON PELICULA EFG 30 comprimidosTOWA PHARMACEUTICAL, S.A. 30 comprimidos €92.10 30 €3.07 €1,121 Código Nacional 714870AEMPS CIMA, registration 81743
FEMARA 2,5 mg COMPRIMIDOS RECUBIERTOS CON PELICULA, 30 comprimidosDIFARMED, S.L.U 30 comprimidos €92.10 30 €3.07 €1,121 Código Nacional 720902AEMPS CIMA, registration 303848-10-2001
LETROZOL ALMUS PHARMA 2,5 MG COMPRIMIDOS RECUBIERTOS CON PELICULA EFG, 30 comprimidosALMUS FARMACEUTICA, S.A.U. 30 comprimidos €92.10 30 €3.07 €1,121 Código Nacional 723930AEMPS CIMA, registration 83555
LETROZOL MABO 2,5 MG COMPRIMIDOS RECUBIERTOS CON PELICULA EFG, 30 comprimidos (Blister Al-PVC/PE/PVDC)MABO-FARMA, S.A. 30 comprimidos €92.10 30 €3.07 €1,121 Código Nacional 727472AEMPS CIMA, registration 84689
LETROZOL AUROVITAS 2,5 MG COMPRIMIDOS RECUBIERTOS CON PELICULA EFG, 30 comprimidosAUROVITAS SPAIN, S.A.U 30 comprimidos €92.10 30 €3.07 €1,121 Código Nacional 729926AEMPS CIMA, registration 85626
LETROZOL TARBIS FARMA 2,5 MG COMPRIMIDOS RECUBIERTOS CON PELICULA EFG, 30 comprimidos (Alu-PVC/PE/PVdC)TARBIS FARMA, S.L. 30 comprimidos €92.10 30 €3.07 €1,121 Código Nacional 730764AEMPS CIMA, registration 85894
LETROZOL TARBIS FARMA 2,5 MG COMPRIMIDOS RECUBIERTOS CON PELICULA EFG, 30 comprimidos (Alu-Alu)TARBIS FARMA, S.L. 30 comprimidos €92.10 30 €3.07 €1,121 Código Nacional 730765AEMPS CIMA, registration 85894
FEMARA 2,5 mg COMPRIMIDOS RECUBIERTOS CON PELICULA, 30 comprimidosECOFAR PRODUCTOS, S.L. 30 comprimidos €92.10 30 €3.07 €1,121 Código Nacional 732457AEMPS CIMA, registration 30384-08-10-2001IP1
FEMARA 2,5 mg COMPRIMIDOS RECUBIERTOS CON PELICULA, 30 comprimidosMELYFARMA, S.L. 30 comprimidos €92.10 30 €3.07 €1,121 Código Nacional 732583AEMPS CIMA, registration 20020268
SYBALI 2,5 MG COMPRIMIDOS RECUBIERTOS CON PELICULA EFG, 30 comprimidosADAMED LABORATORIOS, S.L.U 30 comprimidos €92.10 30 €3.07 €1,121 Código Nacional 763958AEMPS CIMA, registration 89215
FEMARA 2,5 MG COMPRIMIDOS RECUBIERTOS CON PELICULA, 30 comprimidosMELYFARMA, S.L. 30 comprimidos €92.10 30 €3.07 €1,121 Código Nacional 764129AEMPS CIMA, registration 837871425042018
FEMARA 2,5 MG COMPRIMIDOS RECUBIERTOS CON PELICULA, 30 comprimidosABACUS MEDICINE A/S 30 comprimidos €92.10 30 €3.07 €1,121 Código Nacional 766805AEMPS CIMA, registration 837871425042018IP
LETROZOL STADA 2,5 MG COMPRIMIDOS RECUBIERTOS CON PELICULA EFG, 30 comprimidosMELYFARMA, S.L. 30 comprimidos €92.10 30 €3.07 €1,121 Código Nacional 770218AEMPS CIMA, registration 689730000
LOXIFAN 2,5MG 30 COMPRIMIDOS RECUBIERTOS PELICULAESTEVE PHARMACEUTICALS, S.A. 30 COMPRIMIDOS €92.10 30 €3.07 €1,121 Código Nacional 844696AEMPS CIMA, registration 62079
SYBALI 2,5 MG COMPRIMIDOS RECUBIERTOS CON PELICULA EFG, 28 comprimidosADAMED LABORATORIOS, S.L.U 28 comprimidos €85.97 28 €3.07 €1,121 Código Nacional 768205AEMPS CIMA, registration 89215

United Kingdom

Drug Tariff basic price paid to the pharmacy, excluding VAT (Part VIIIA Category M). Source [13][14], read on 9 October 2026. ATC match: ATC code of the virtual product (VMP) in the dm+d.

Show the 1 pack
ProductPackPrice DDD per packCost per DDDAnnual cost at the WHO standard doseSource line
Letrozole 2.5mg tablets 28 tablet £2.14 28 £0.08 £27.90€32.91 VMPP SNOMED 3668911000001104dm+d browser, VMP 3692

References

  1. WHO Collaborating Centre for Drug Statistics Methodology. ATC/DDD Index 2026 [Internet]. Oslo: Norwegian Institute of Public Health; [updated 2026 Jan 20; cited 2026 Oct 9]. Available from: https://atcddd.fhi.no/atc_ddd_index/
  2. World Health Organization. Electronic Essential Medicines List (eEML) [Internet]. Geneva: WHO; [cited 2026 Oct 9]. Available from: https://list.essentialmeds.org/
  3. European Central Bank. Euro foreign exchange reference rates, 9 October 2026 [Internet]. Frankfurt am Main: ECB; 2026 [cited 2026 Oct 9]. Available from: https://www.ecb.europa.eu/stats/policy_and_exchange_rates/euro_reference_exchange_rates/html/index.en.html
  4. Base de données publique des médicaments [Internet]. Paris: Ministère du Travail, de la Santé, des Solidarités et des Familles; 2026 [updated 2026 Oct 8; cited 2026 Oct 9]. Available from: https://base-donnees-publique.medicaments.gouv.fr/telechargement
  5. Agencia Española de Medicamentos y Productos Sanitarios. CIMA: Centro de información de medicamentos [Internet]. Madrid: AEMPS; [cited 2026 Oct 9]. Available from: https://cima.aemps.es/cima/
  6. European Medicines Agency. Download medicine data [Internet]. Amsterdam: EMA; 2026 [updated 2026 Oct 9; cited 2026 Oct 9]. Available from: https://www.ema.europa.eu/en/medicines/download-medicine-data
  7. PubMed [Internet]. Bethesda (MD): National Library of Medicine (US); [cited 2026 Oct 9]. Available from: https://pubmed.ncbi.nlm.nih.gov/
  8. National Institute for Health and Care Excellence. Technology appraisal guidance [Internet]. London: NICE; [cited 2026 Oct 9]. Available from: https://www.nice.org.uk/guidance/published?ngt=Technology%20appraisal%20guidance
  9. Scottish Medicines Consortium. Medicines advice [Internet]. Glasgow: SMC; [cited 2026 Oct 9]. Available from: https://scottishmedicines.org.uk/medicines-advice/
  10. Gemeinsamer Bundesausschuss. Nutzenbewertung nach § 35a SGB V: Apixaban [Internet]. Berlin: G-BA; [cited 2026 Oct 9]. Available from: https://www.g-ba.de/bewertungsverfahren/nutzenbewertung/
  11. Agencia Española de Medicamentos y Productos Sanitarios. Informes de posicionamiento terapéutico [Internet]. Madrid: AEMPS; [cited 2026 Oct 9]. Available from: https://www.aemps.gob.es/medicamentos-de-uso-humano/evaluacion-de-tecnologias-sanitarias/informes-de-posicionamiento-terapeutico/
  12. Ministerio de Sanidad. Nomenclátor de facturación de octubre 2026 [Internet]. Madrid: Ministerio de Sanidad; 2026 [cited 2026 Oct 9]. Available from: https://www.sanidad.gob.es/profesionales/nomenclator.do
  13. NHS Business Services Authority. Drug Tariff Part VIIIA, October 2026 [Internet]. Newcastle upon Tyne: NHSBSA; 2026 [cited 2026 Oct 9]. Available from: https://www.nhsbsa.nhs.uk/pharmacies-gp-practices-and-appliance-contractors/drug-tariff/drug-tariff-part-viii
  14. NHS Business Services Authority. dm+d browser: NHS dictionary of medicines and devices [Internet]. Newcastle upon Tyne: NHSBSA; [updated 2026 Oct 1; cited 2026 Oct 9]. Available from: https://dmd-browser.nhsbsa.nhs.uk/